Columbia Regional Airport is served by 3 airlines, flying from/to 5 destinationsLongest flight from Columbia Regional Airport is Columbia to 🇺🇸 Kansas City (MKC), which takes around 25 minutes. On an airline like National Airlines. More info on this flight route (COU-MKC).Shortest flight from Columbia Regional Airport is Columbia to 🇺🇸 Kansas City (MKC), which takes around 25 minutes. On an airline like National Airlines. More info on this flight route (COU-MKC).