Southwest Florida International Airport is served by 24 airlines, flying from/to 59 destinationsLongest flight from Southwest Florida International Airport is Fort Myers to 🇺🇸 Denver (DEN), which takes around 4 hours and 20 minutes. On an airline like United Airlines. More info on this flight route (RSW-DEN).Shortest flight from Southwest Florida International Airport is Fort Myers to 🇺🇸 Fort Lauderdale (FLL), which takes around 20 minutes. On an airline like Netjets Aviation. More info on this flight route (RSW-FLL).