San Diego International Airport is served by 32 airlines, flying from/to 43 destinationsLongest flight from San Diego International Airport is San Diego to 🇺🇸 Kailua/Kona (KOA), which takes around 6 hours and 5 minutes. On an airline like Alaska Airlines. More info on this flight route (SAN-KOA).Shortest flight from San Diego International Airport is San Diego to 🇲🇽 Tijuana (TIJ), which takes around 15 minutes. On an airline like Fly Baghdad. More info on this flight route (SAN-TIJ).