San Luis Obispo County Regional Airport is served by 8 airlines, flying from/to 9 destinationsLongest flight from San Luis Obispo County Regional Airport is San Luis Obispo to 🇺🇸 Portland (PDX), which takes around 2 hours and 10 minutes. On an airline like Alaska Airlines. More info on this flight route (SBP-PDX).Shortest flight from San Luis Obispo County Regional Airport is San Luis Obispo to 🇺🇸 Santa Ana (SNA), which takes around 40 minutes. On an airline like Netjets Aviation. More info on this flight route (SBP-SNA).